• Users Online: 46
  • Print this page
  • Email this page
ORIGINAL ARTICLE
Year : 2020  |  Volume : 5  |  Issue : 2  |  Page : 48-52

Histopathologic changes in aborted placenta


1 Department of Pathology, Faculty of Medicine, University of Benghazi, Benghazi, Libya
2 Department of Family and Community Medicine, Faculty of Medicine, University of Benghazi, Benghazi, Libya

Correspondence Address:
A R. Guheina Ashour
Department of Pathology, Faculty of Medicine, University of Benghazi, Benghazi
Libya
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/LIUJ.LIUJ_7_20

Rights and Permissions

Introduction: Histopathological examination of the placenta with clinical implications helps to make the diagnosis and deduce the cause of abortion, fetal mortality, morbidity, and pregnancy complications. Aim: This study aims to determine the frequencies and types of abnormalities of the chorionic villi in the aborted placentae.Materials and Methods: All specimens of products of conception submitted to a private histopathology laboratory in Benghazi during the period (from January 01, 2016 to December 31, 2018) were formalin-fixed, paraffin-embedded, and histopathology reviewed using hematoxylin and eosin stain under light microscopy. The data collected and statistically analyzed using SPSS version 22. Results: The study involved 92 specimens, of which 86 were abnormal and the pathological changes include partial mole (48%), hydropic changes (19%), increased vascularity (chorioangiosis) (13%), fibrosis (10%), numerous Hofbauer macrophages (8%), and abnormal premature calcification (2%). The rest of the specimens (6.5%) were normal placentae. Most of the cases of partial mole (73%) were at the age group of ≥30 years, and cases of abnormal premature calcification were at the age of >40 years. Conclusion: The histopathologic examination is an important tool for diagnosing the placental abnormalities. Most cases of abortion have abnormalities in chorionic villi; the most common abnormality is the partial mole, followed by hydropic change, then increased vascularity (chorioangiosis), fibrosis, and numerous Hofbauer macrophages. Abnormal premature calcification is the least finding. Partial mole occurs at an older age group of ≥30 years.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed689    
    Printed29    
    Emailed0    
    PDF Downloaded45    
    Comments [Add]    

Recommend this journal